Haftchenary, Sina’s team published research in ACS Combinatorial Science in 2016-09-12 | CAS: 4042-43-7

ACS Combinatorial Science published new progress about Amino alcohols, chiral Role: RCT (Reactant), RACT (Reactant or Reagent). 4042-43-7 belongs to class oxazolidine, name is (R)-4-Methyloxazolidin-2-one, and the molecular formula is C4H7NO2, Safety of (R)-4-Methyloxazolidin-2-one.

Haftchenary, Sina published the artcileEfficient Routes to a Diverse Array of Amino Alcohol-Derived Chiral Fragments, Safety of (R)-4-Methyloxazolidin-2-one, the main research area is amino alc chiral fragment reaction; oxazolidinone morpholinone lactam sultam preparation reaction; amino alcohols; chiral fragments; drug discovery; fragment-based lead discovery.

Efficient syntheses of chiral fragments derived from chiral amino alcs. are described. Several unique scaffolds were readily accessed in 1-5 synthetic steps leading to 45 chiral fragments, including five- to seven-membered oxazolidinones, morpholinones, lactams, and sultams. These fragments have mol. weights ranging from 100 to 255 Da and are soluble in water (0.085 to >15 mM).

ACS Combinatorial Science published new progress about Amino alcohols, chiral Role: RCT (Reactant), RACT (Reactant or Reagent). 4042-43-7 belongs to class oxazolidine, name is (R)-4-Methyloxazolidin-2-one, and the molecular formula is C4H7NO2, Safety of (R)-4-Methyloxazolidin-2-one.

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem