Extracurricular laboratory:new discovery of Oxazolidin-2-one

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 497-25-6

Electric Literature of 497-25-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2. In a article,once mentioned of 497-25-6

Efficient CuI/1,10-phen-catalyzed three-component cascade reaction of propargylic alcohols, CO2, and 2-aminoethanols has been firstly developed for the thermodynamically favourable preparation of 2-oxazolidinones. In the presence of commercially available CuI, 1,10-phen (1,10-phenanthroline) and t-BuOK, the cascade reaction afforded the desired products in good to excellent yields with a broad substrate scope (14 examples). The predicted copper complex Cu2I2(phen)2 in situ formed from CuI and 1,10-phen could activate the triple bond through coordination. The isolation of alpha-alkylidene cyclic carbonate as the reaction intermediate suggests that the carboxylative cyclization of propargylic alcohol with CO2, followed by ring-opening reaction, is involved in the one-pot three-component cascade reaction.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 497-25-6

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H743NO – PubChem