In an article, author is Mazi, Wafa, once mentioned the application of 16251-45-9, Name: (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, molecular formula is C10H11NO2, molecular weight is 177.2, MDL number is MFCD00066226, category is oxazolidines. Now introduce a scientific discovery about this category.
A near-infrared fluorescent probe based on a hemicyanine dye with an oxazolidine switch for mitochondrial pH detection
A near-infrared fluorescent probe (AH+) has been prepared by incorporating an oxazolidine switch into a near-infrared hemicyanine dye. The probe shows fast and sensitive responses to pH from an oxazolidine switch to the hemicyanine dye upon pH decreases from 10.0 to 5.0. The probe shows good photostability, low cytotoxicity, and reversible fluorescence responses to pH changes with a pK(a) value of 7.6. It has been successfully used to determine pH changes in mitochondria.
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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem