99395-88-7, (S)-4-Phenyloxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Sodium hydride (60% by weight liquid paraffin dispersion, 270 mg, 6.75 mmol) was added to a tetrahydrofuran (15 mL) solution of (S) -4-phenyloxazolidin-2-one (1.00 g, 6.14 mmol) In addition,After stirring at 0 C. for 20 minutes, 2-chloroacetyl chloride (0.538 mL, 6.75 mmol) was added at 0 C.,And the mixture was stirred at 0 C. for 1 hour.Saturated aqueous sodium hydrogen carbonate solution (10 mL) was added to the reaction solution, and the obtained aqueous solution was extracted three times with ethyl acetate,The organic layer was washed with a saturated aqueous sodium chloride solution,Dried over anhydrous sodium sulfate and filtered, and the filtrate was concentrated under reduced pressure. The obtained residue was purified by column chromatography (silica gel, n-hexane / ethyl acetate)(S) -3- (2-chloroacetyl) -4-phenyloxazolidin-2-one(979 mg, 4.11 mmol, 67%)As a white powder., 99395-88-7
As the paragraph descriping shows that 99395-88-7 is playing an increasingly important role.
Reference£º
Patent; Toray Industries, Inc.; Adachi, Youhei; Taguri, Tomonori; (23 pag.)JP2018/172309; (2018); A;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem