Downstream synthetic route of 152305-23-2

As the paragraph descriping shows that 152305-23-2 is playing an increasingly important role.

152305-23-2, (S)-4-(4-Aminobenzyl)oxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,152305-23-2

Example – J: Preparation of (S)-4-(4-methylphenyl hydrazine)-., 3-oxazolidin-2-one (S)-4-4-(amino benzyl)-l,3- oxazolidine-2-one (10 g, 0.052 moles) is suspended in water (20 ml) and cooled to -5¡ãC. A solution of sodium Nitrite (4.2 g; 0.06 moles in 42.0 ml water) is slowly added to the above solution and stirred for 45 min. at -5 to 00C.The above reaction mixture is added lot- wise at 5¡ãC to 10¡ãC to a solution of Triphenyl phosphine (40.91 g; 0.155 moles) in methanol (120.0 ml) and diethyl ether (40.0 ml).The reaction mixture is stirred at room temperature for about 8hrs. After the reaction is completed the resulted dark brown oily layer is separated and evaporated under vacuum. The obtained residue is triturated with chloroform and methanol to get the desired product (35.0g).

As the paragraph descriping shows that 152305-23-2 is playing an increasingly important role.

Reference£º
Patent; MATRIX LABORATORIES LTD; WO2007/83320; (2007); A2;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem