Discovery of Oxazolidin-2-one

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 497-25-6, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2

3-[(4-Substituted) (2-oxo-1,3-oxazolidin-3-yl)-phosphoryl]-1,3-oxazolidin- 2-ones (4a-j) were synthesized through a two-step process. Bis-(2-oxo-1,3- oxazolidin-3-yl)-phosphonic chloride (2) prepared by the reaction of two moles of oxazolidin-2-one (1) with phosphorus oxychloride in dry tetrahydrofuran in the presence of triethylamine and treatment with various heterocyclic aromatic and aliphatic amines under the same experimental conditions afforded the title compounds (4a-j). They were characterized by elemental analysis, IR, NMR ( 1H, 13C and 31P) and mass spectroscopy. Their antimicrobial activities were also evaluated.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H928NO – PubChem