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Asymmetric dihydroxylation of beta,beta- disubstituted enamides afforded chiral tertiary-alcohol-containing alpha-hydroxyaldehydes and 1,2-diols with high enantioselectivity (see scheme). This method was applied to the total synthesis of the antifungal natural product (+)-tanikolide, as well as the synthesis of an intermediate enroute to (S)-oxybutynin.
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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H565NO – PubChem