Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one, is researched, Molecular C5H6N2O2, CAS is 1194-22-5, about Synthesis, structure, and properties of oligo-tridentate ligands; covalently assembled precursors of coordination arrays.Category: oxazolidine.
Oligo-tridentate ligands based on alternating pyridines and pyrimidines, e.g., I (R = H, Ph, 9-anthryl, R’ = H, Me, CH2Br) and II (R = H, Me, Ph), were synthesized by Stille-type carbon-carbon bond-forming reactions. The terpyridine-like sites are designed to coalign upon metal complexation, giving rise to organized and rigidly spaced metal ions. Peripheral functionalization of the basic bis-tridentate framework was explored. The heterocycles in the ligands are in an all-trans conformation about the interannular bonds as indicated by comparison of their 1H NMR spectra. An x-ray crystal structure anal. of the nonchiral tris-tridentate ligand II (R = H) reveals a helical structure in the solid state. The seven heterocycles form a helical structure with resulting overlap of the terminal pyridines. Their centroid-to-centroid distance is 4.523 Å with 38.8° between the planes. NMR investigations support a helical conformation in solution as well. Electrochem. and UV absorption measurements indicate that the LUMO resides on the pyrimidine moiety of the ligands.
Different reactions of this compound(6-Hydroxy-2-methylpyrimidin-4(3H)-one)Category: oxazolidine require different conditions, so the reaction conditions are very important.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem