Category: oxazolidines

Electric Literature of 99395-88-7, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 99395-88-7, Name is (S)-4-Phenyloxazolidin-2-one, SMILES is [C@H]1(NC(OC1)=O)C2=CC=CC=C2, belongs to oxazolidines compound. In a article, author is Radulovic, Niko S., introduce new discover of the category.

Two goitrogenic 1,3-oxazolidine-2-thione derivatives from Brassicales taxa: Challenging identification, occurrence and immunomodulatory effects

1,3-Oxazolidine-2-thione derivatives are glucosinolate-related food constituents known to impart (thyreo)toxic properties to some cruciferous vegetables. In this work, 5,5-dimethyl-1,3-oxazolidine-2-thione and (-)-(R)-5phenyl-1,3-oxazolidine-2-thione, known goitrogens, were isolated from Draba lasiocarpa Rochel (Brassicaceae) and Reseda luteoia L. (Resedaceae), respectively, and were fully spectrally characterized. Subsequently, the occurrence of the two 1,3-oxazolidine-2-thiones was verified in six additional taxa out of in total 78 screened Serbian Brassicales taxa. The stereochemistry of 5-phenyl-1,3-oxazolidine-2-thione was inferred from nuclear magnetic resonance experiments with a chiral lanthanide-shift reagent, employed in this work for the first time for this type of compounds. Unexpectedly, during gas chromatography, 5-phenyl-1,3-oxazolidine-2-thione underwent an unreported thermal core isomerization (1,3-oxazolidine-2-thione to 1,3-thiazolidine-2-one). These goitrogenic volatile glucosinolate products were tested for their effect on rat macrophage viability (three assays) and nitric oxide production. It was shown that the compounds displayed different levels of cytotoxicity. All tested compounds caused a significant lactate dehydrogenase leakage, but only (R)-5-phenyl-1,3-oxazolidine-2thione statistically significantly reduced macrophage mitochondrial activity, whereas the racemic 5-phenyl-1,3oxazolidine-2-thione and 5,5-dimethyl-1,3-oxazolidine-2-thione had little or no effect. Again only (R)-5-phenyl1,3-oxazolidine-2-thione exerted nitric oxide production-inhibiting properties, suggesting the higher immunomodulatory potential of this enantiomer compared with its antipode and racemic mixture.

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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Product Details of 84793-24-884793-24-8, Name is Ethyl (S)-2-[(S)-4-Methyl-2,5-dioxo-3-oxazolidinyl]-4-phenylbutanoate, SMILES is O=C(OCC)[C@@H](N([C@H]1C)C(OC1=O)=O)CCC2=CC=CC=C2, belongs to oxazolidines compound. In a article, author is Wang, Yanmei, introduce new discover of the category.

Synthesis of Amphiphilic Copolymer Having Acid-Labile Bicyclo Bisoxazolidine in the Side Chain for Controlled Release of Fragrance Aldehyde

A metharylate monomer having an octanal-derived bicyclo bisoxazolidine (BBOX) moiety was synthesized and was radically copolymerized with a methacrylate having a hydrophilic poly(ethylene glycol) chain to obtain an amphiphilic copolymer having the BBOX moieties as hydrophobic side chains. The BBOX moieties were stable for 7 days at pH 7.0, whereas they were gradually hydrolyze at pH 5.0 to release octanal continuously for 7 days, confirming the potential applicability of the copolymer to a polymeric pro-fragrance that can release aldehyde-type fragrance molecules slowly for a long period. (C) 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 49:1881-1886, 2011

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 84793-24-8. Product Details of 84793-24-8.

Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Synthetic Route of 84793-24-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 84793-24-8, Name is Ethyl (S)-2-[(S)-4-Methyl-2,5-dioxo-3-oxazolidinyl]-4-phenylbutanoate, SMILES is O=C(OCC)[C@@H](N([C@H]1C)C(OC1=O)=O)CCC2=CC=CC=C2, belongs to oxazolidines compound. In a article, author is Luk’yanov, B. S., introduce new discover of the category.

Structural studies of 1,3-oxazolidine-containing spiropyrans

New 3′-(4-chlorophenyl)-5 ‘,5′-dimethyl-2′-oxospiro[(2H)-chromene-2,4’-1,3-oxazol-idine] was synthesized to study the donor influence of the chlorine atom at the N-phenyl substituent on the structure and photochromic properties of 1,3-oxazolidine-containing spiro-pyrans. Photochemical properties of synthesized 1,3-oxazolidine derivatives were studied at room temperature in toluene. The X-ray diffraction parameters for the new compound were compared with the data obtained earlier for similar spiropyrans.

Synthetic Route of 84793-24-8, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 84793-24-8 is helpful to your research.

Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Related Products of 16251-45-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, SMILES is O=C1O[C@H](C2=CC=CC=C2)[C@H](C)N1, belongs to oxazolidines compound. In a article, author is Lu, Zheng, introduce new discover of the category.

Convenient approach to chiral 4-monosubstituted 1,3-oxazolidine-2-thiones

Chiral 4-monosubstituted 1,3-oxazolidine-2-thiones are regarded as one of the modified version of Evans auxiliaries in asymmetric aldol condensation, which can generate two adjacent chiral carbon centers in one time They have advantages over Evans auxiliaries in some aspects, however, their application is highly limited by their preparation approaches as toxic or flammable chemicals are involved. Here, a mild and applicable procedure for preparing the chiral oxazolidine-2-thione auxiliaries has been developed in this article. Potassium ethylxanthate and the corresponding chiral amino alcohols as the starting material in absolute ethanol are mixed and the mixture are heated under reflux for 1h in open air to provide 1,3-oxazolidine-2-thiones chiral auxiliaries in moderate to excellent yields. [GRAPHICS] .

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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Synthetic Route of 84793-24-8, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 84793-24-8, Name is Ethyl (S)-2-[(S)-4-Methyl-2,5-dioxo-3-oxazolidinyl]-4-phenylbutanoate, SMILES is O=C(OCC)[C@@H](N([C@H]1C)C(OC1=O)=O)CCC2=CC=CC=C2, belongs to oxazolidines compound. In a article, author is Qin, Shaoheng, introduce new discover of the category.

Synthesis of spiro 1,3-oxazolidines via palladium-catalyzed [3+2] cycloaddition of vinyl epoxides with cyclohexadienimines

A palladium-catalyzed chemoselective [3 + 2] cycloaddition of vinyl epoxide with cyclohexadienimines was developed. The reaction gave rise to a range of spiro 1,3-oxazolidines in moderate to good yields. (C) 2020 Published by Elsevier B.V. on behalf of King Saud University.

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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: 99395-88-7, 99395-88-7, Name is (S)-4-Phenyloxazolidin-2-one, SMILES is [C@H]1(NC(OC1)=O)C2=CC=CC=C2, belongs to oxazolidines compound. In a document, author is Nogueira, Thais C. M., introduce the new discover.

A New Synthesis of Chiral Oxazolidinones from the Amino Acid L-serine

Cyclization of the (4S)-PhCH2OCONHCH(CH2OH) CONHN=CH-aryl, obtained in 4 steps from L-serine, on treatment with MeI and potassium carbonate, generates the chiral oxazolidinones, (4S)-N’-[(E)-(phenyl) methylidene]-N-methyl-2-oxo-1,3-oxazolidine-4-carbohydrazides. Overall the formation of the (4S)-N’-[(E)-(phenyl) methylidene]-Nmethyl-2-oxo-1,3-oxazolidine-4-carbohydrazides from L-serine occurs with retention of configuration, as confirmed by Xray crystallography. In contrast, the reaction of the N-Boc analogues, (4S)-t-BuOCONHCH(CH2OH) CONHN=CH-aryl, on treatment with MeI / K2CO3, simply leads to N-methylation without cyclization and without loss of the Boc protecting group to give (4S)-t-BuOCONMeCH(CH2OH) CONHN=CH-aryl. The difference between the Boc and Cbz derivatives is striking and is probably linked to the greater bulk of the Boc group blocking the intramolecular acyl transfer.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 99395-88-7 is helpful to your research. Recommanded Product: 99395-88-7.

Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 99395-88-7, Name is (S)-4-Phenyloxazolidin-2-one, molecular formula is , belongs to oxazolidines compound. In a document, author is Fryzlewicz, Agnieszka, Recommanded Product: (S)-4-Phenyloxazolidin-2-one.

Regio- and stereoselective synthesis of nitrofunctionalized 1,2-oxazolidine analogs of nicotine

(E)-3,3,3-Trichloro-1-nitroprop-1-ene undergoes [3+2] cycloaddition reaction with N-aryl(pyridin-3-yl) nitrones under mild conditions. The reaction is fully regio- and stereoselective and gives expected nitro-substituted nicotine analogs with 3,4-cis-4,5-trans-stereoconfiguration.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 99395-88-7, in my other articles. Recommanded Product: (S)-4-Phenyloxazolidin-2-one.

Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 6704-31-0, Name is Oxetan-3-one, molecular formula is C3H4O2. In an article, author is Keiko, N. A.,once mentioned of 6704-31-0, COA of Formula: C3H4O2.

Regioselectivity of the Hydrolysis of 2-(1-Alkoxyvinyl)-Substituted Imidazolidines, 1,3-Thiazolidines, and 1,3-Oxazolidines

2-(1-Alkoxyvinyl)-1,3-thiazolidines reacted with H2O or D2O in the presence of 105 mol % of p-toluenesulfonic acid or trifluoroacetic acid (20 degrees C, 1 h) to give 2-acetyl-1,3-thiazolidine in quantitative yield. 2-(1-Alkoxyvinyl)-3,5-diphenylimidazolidines underwent hydrolysis in the presence of 20 mol % of an acid (20 degrees C, 24 h) at the vinyloxy group with high regioselectivity yielding 2-acetylimidazolidines. Hydrolysis of 2-(1-alkoxyvinyl)-3-phenyl-1,3-oxazolidines in the presence of 10 mol % of p-toluenesulfonic acid (20 degrees C, 5 days) takes two pathways, one of which involves the endocyclic C-O bond with ring opening and the other involves the vinyloxy group to produce 2-acetyl-3-phenyl-1,3-oxazolidine. Unlike phenyl-substituted 1,3-thiazolidines and imidazolidines, hydrolysis of their 3-methyl-and 3,5-dimethyl-substituted analogs in acid medium occurs mainly via ring opening. The observed hydrolysis pathways were interpreted in terms of B3PW91/6-311G(d,p) quantum-chemical calculations.

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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

In an article, author is Gordillo, Paola G., once mentioned the application of 90319-52-1, Name is (R)-4-Phenyloxazolidin-2-one, molecular formula is C9H9NO2, molecular weight is 163.1733, MDL number is MFCD00192393, category is oxazolidines. Now introduce a scientific discovery about this category, Recommanded Product: 90319-52-1.

Oxazolidine Sulfur Ylides Derived from Phenylglycinol for the Specific and Highly Diastereoselective Synthesis of Aryl and Alkyl trans-Epoxyamides

Aryl and alkyl chiral oxazolidine sulfonium salts with cis and trans dispositions derived from (-)-(R)-2-phenylglycinol were demonstrated to be good to excellent chiral auxiliaries for the diastereoselective synthesis of (2R,3S)-trans-epoxyamides. Interestingly, the diastereoselective outcome depends on the stereochemistry of the chiral center at the C-4 position of the oxazole moiety. The stereoselectivities were consistent even for aliphatic aldehydes.

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Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem

 

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Kang, Wu, once mentioned the application of 99395-88-7, Name is (S)-4-Phenyloxazolidin-2-one, molecular formula is C9H9NO2, molecular weight is 163.1733, MDL number is MFCD00043396, category is oxazolidines. Now introduce a scientific discovery about this category, Category: oxazolidines.

A simple oxazolidine linker for solid-phase synthesis of peptide aldehydes

A very simple and cheap linker has been used for solid-phase synthesis of peptide aldehydes. Protected amino acid aldehydes are immobilized on 2-Cl(trt) resin as oxazolidine formation via diethanolamine. After classical Fmoc SPPS, treatment of the resin with AcOH/DCM/H2O (8:1:1) affords peptide aldehydes in high yield and purity. (C) 2011 Elsevier Ltd. All rights reserved.

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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem