Category: 888329-88-2

Unusual mechanisms in Claisen rearrangements: an ionic fragmentation leading to a meta-selective rearrangement was written by Maryasin, Boris;Kaldre, Dainis;Galaverna, Renan;Klose, Immo;Ruider, Stefan;Drescher, Martina;Kaehlig, Hanspeter;Gonzalez, Leticia;Eberlin, Marcos N.;Jurberg, Igor D.;Maulide, Nuno. And the article was included in Chemical Science in 2018.Reference of 888329-88-2 This article mentions the following:

A mechanistic investigation of the acid-catalyzed redox-neutral oxoarylation reaction of ynamides using electrospray ionization mass-spectrometry (ESI-MS) and quantum chem. calculations (DFT and MP2) is presented. This study reveals the diversity of pathways and products available from an otherwise deceptively simple-looking, classical transformation: fragmentation, an unusual meta-arylation and competing α-carbonyl cation pathways are some of the alternatives unveiled by ESI-MS and mechanistic experiments Detailed calculations explain the observed trends and rationalize the results. In the experiment, the researchers used many compounds, for example, 3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2Reference of 888329-88-2).

3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Reference of 888329-88-2

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Metal-Free Synthesis of Highly Substituted Pyridines by Formal [2+2+2] Cycloaddition under Mild Conditions was written by Xie, Lan-Gui;Shaaban, Saad;Chen, Xiangyu;Maulide, Nuno. And the article was included in Angewandte Chemie, International Edition in 2016.Recommanded Product: 3-(Phenylethynyl)oxazolidin-2-one This article mentions the following:

The synthesis of pyridines through direct intermol. cycloaddition of alkynes and nitriles is a contemporary challenge in organic synthesis. A Bronsted acid mediated formal [2+2+2] cycloaddition of heteroalkynes and nitriles was developed that proceeds under mild conditions. This constitutes a modular approach to highly substituted pyridine cores. In the experiment, the researchers used many compounds, for example, 3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2Recommanded Product: 3-(Phenylethynyl)oxazolidin-2-one).

3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Recommanded Product: 3-(Phenylethynyl)oxazolidin-2-one

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem