Category: 70-23-5

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 70-23-5, is researched, SMILESS is O=C(OCC)C(CBr)=O, Molecular C5H7BrO3Journal, Article, Combinatorial Chemistry & High Throughput Screening called Green synthesis of 4H-pyran derivatives using Fe3O4-MNPs as efficient nanocatalyst: study of antioxidant activity, Author is Shafaei, Faezeh; Najar, Asef H., the main research direction is iron oxide magnetic nanoparticle preparation; dialkyl oxo dihydroindenopyran dicarboxylate green preparation antioxidant; ninhydrin haloketone dialkyl acetylenedicarboxylate triphenylphosphine multicomponent iron oxide nanocatalyst; Diels-Alder reactions; Fe3O4-MNPs; Ninhydrine; Pyran; green synthesis; α-haloketones.Recommanded Product: Ethyl 3-bromo-2-oxopropanoate.

A series of dialkyl 4-(oxo-alkoxy/aryl)-5-oxo-4,5-dihydroindeno[1,2-b]pyran-2,3-dicarboxylates I [R = CO2Et, 4-MeC6H4, 4-BrC6H4, etc.; R1 = Me, Et] was synthesized via a multicomponent reaction of ninhydrin, α-haloketones, dialkyl acetylenedicarboxylates and triphenylphosphine in the presence of iron oxide magnetic nanoparticles (Fe3O4-MNPs) as efficient nanocatalyst in ethanol at room temperature The biosynthesis of Fe3O4-MNPs was achieved using Clover Leaf water extract In addition, antioxidant activity was examined for some of the compounds I [R = CO2Et, 4-MeC6H4, 4-MeOC6H4, 4-O2NC6H4; R1 = Me, Et] employing DPPH radical scavenging and ferric reduction activity potential (FRAP) experiment and compared results with synthetic antioxidants (TBHQ and BHT). Compound I [R = CO2Et; R1 = Et] showed excellent radical trapping activity and good reducing activity relative to standards (BHT and TBHQ). Some advantages of this procedure were easiness of reaction workup and seperation of products by simply filtration. Fe3O4-MNPs displayed a good improvement in the yield of the product and showed significant reusable activity.

From this literature《Green synthesis of 4H-pyran derivatives using Fe3O4-MNPs as efficient nanocatalyst: study of antioxidant activity》,we know some information about this compound(70-23-5)Recommanded Product: Ethyl 3-bromo-2-oxopropanoate, but this is not all information, there are many literatures related to this compound(70-23-5).

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Hamedani, Naghmeh Faal; Azad, Leila; Shafiee, Shahin; Noushin, Annataj published an article about the compound: Ethyl 3-bromo-2-oxopropanoate( cas:70-23-5,SMILESS:O=C(OCC)C(CBr)=O ).Name: Ethyl 3-bromo-2-oxopropanoate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:70-23-5) through the article.

The multicomponent reaction of aldehydes, benzoylisothiocyanate and alkyl bromides in the presence of ammonium acetate, sodium cyanide and a catalytic amount of KF/Clinoptilolite nanoparticles (KF/CP NPs) in the water at 100°C was investigated. In these reactions, thiazole I [R= H, Me, i-Pr; R1 = ethoxycarbonyl, 4-methoxyphenyl, 4-bromophenyl] were produced in good to excellent yields and short time. Also, the antioxidant activity was studied for some newly synthesized compounds using the DPPH radical trapping and reducing of ferric ion experiments and compared the results with synthetic antioxidants (TBHQ and BHT). As a result, the compounds I [R= i-Pr; R1 = ethoxycarbonyl] showed excellent DPPH radical trapping and reducing the strength of ferric ion. These compounds I [R= H, Me, i-Pr; R1 = ethoxycarbonyl, 4-methoxyphenyl, 4-bromophenyl] have biol. potential because of the thiazole core. For this reason, the antimicrobial activity of some synthesized compounds I [R= H, Me, i-Pr; R1 = ethoxycarbonyl, 4-methoxyphenyl, 4-bromophenyl] was studied by employing the disk diffusion test on Gram-pos. bacteria and Gram-neg. bacteria. The results of the disk diffusion test showed that these compounds I [R= H, Me, i-Pr; R1 = ethoxycarbonyl, 4-methoxyphenyl, 4-bromophenyl] prevented bacterial growth.

From this literature《Green Synthesis of Thiazole Derivatives using Multi-component Reaction of Aldehydes, Isothiocyanate and Alkyl Bromides: Investigation of Antioxidant and Antimicrobial Activity》,we know some information about this compound(70-23-5)Name: Ethyl 3-bromo-2-oxopropanoate, but this is not all information, there are many literatures related to this compound(70-23-5).

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Reference of Ethyl 3-bromo-2-oxopropanoate. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Ethyl 3-bromo-2-oxopropanoate, is researched, Molecular C5H7BrO3, CAS is 70-23-5, about Four-component green synthesis of benzochromene derivatives using nano-KF/clinoptilolite as basic catalyst: study of antioxidant activity. Author is Ezzatzadeh, Elham; Hossaini, Zinatossadat.

An efficient procedure for the synthesis of benzochromene derivatives I (R = Me, Et, Ph, 4-MeC6H4, 4-MeOC6H4; R1 = COOEt, 4-MeC6H4, 4-MeOC6H4; R2 = Me, Et) employing 1-(6-hydroxy-2-isopropenyl-1-benzofuran-yl)-1-ethanone (euparin), aldehydes, alkyl bromides, dialkyl acetylenedicarboxylate and triphenylphosphine in the presence of KF/CP NPs as a heterogeneous base nano-catalyst in water at 80° is investigated. Also, the antioxidant activity of some synthesized compounds was studied. The workup of mixture of reaction is simple, and the products can be separated easily by filtration. KF/CP NPs showed a good improvement in the yield of the product and displayed significant reusable activity.

If you want to learn more about this compound(Ethyl 3-bromo-2-oxopropanoate)Reference of Ethyl 3-bromo-2-oxopropanoate, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(70-23-5).

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Application In Synthesis of Ethyl 3-bromo-2-oxopropanoate. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Ethyl 3-bromo-2-oxopropanoate, is researched, Molecular C5H7BrO3, CAS is 70-23-5, about Syntheses of Novel Tetrasubstituted Thiophenes from Benzene-1,2-Diamines, Ethyl Bromopyruvate, Malononitrile, and Aryl Isothiocyanates. Author is Piltan, Mohammad.

Synthesis of amino(oxo-dihydroquinoxalinyl)(phenylamino)thiophene-carbonitrile derivatives I [R = H, Me, Cl; R1 = 2-MeOC6H4, 4-NO2C6H4, Et, Ph] was reported via sequential base mediated condensation of malononitrile with aryl isothiocyanates followed by S-alkylation with 3-(bromomethyl)quinoxalin-2(1H)-one compounds and concurrent intramol. enamine type condensation of S-alkylated compounds in excellent yields.

If you want to learn more about this compound(Ethyl 3-bromo-2-oxopropanoate)Application In Synthesis of Ethyl 3-bromo-2-oxopropanoate, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(70-23-5).

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Application In Synthesis of Ethyl 3-bromo-2-oxopropanoate. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Ethyl 3-bromo-2-oxopropanoate, is researched, Molecular C5H7BrO3, CAS is 70-23-5, about Design, synthesis, in vitro evaluation and molecular docking study of N’-arylidene imidazo[1,2-a]pyridine -2-carbohydrazide derivatives as novel tyrosinase inhibitors.

A novel series of imidazo[1,2-a]pyridine 2-carbohydrazide derivatives bearing different arylidene pendants I [R = 4-OH, 2-MeO, 3-OH-4-MeO, etc.] were designed, synthesized and evaluated for their inhibitory activity against mushroom tyrosinase. It was found that compounds I [R = 3-NO2, 4-OH] exhibited the best tyrosinase inhibitory activity with IC50 values of 7.19 and 8.11μM, resp. These results were comparable to that of kojic acid as the reference drug (IC50 = 9.64±0.5μM). Addnl., mol. docking anal. was performed to study the interactions and binding modes of compounds I [R = 3-NO2, 4-OH, 2,4-di-OH] which showed the potential of two critical pi-pi interactions with His263 and Phe264 in the active site of tyrosinase. The results indicated that compounds I [R = 3-NO2, 4-OH] could be introduced as potent tyrosinase inhibitors that might serve as promising candidates in medicine, cosmetics or food industry.

If you want to learn more about this compound(Ethyl 3-bromo-2-oxopropanoate)Application In Synthesis of Ethyl 3-bromo-2-oxopropanoate, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(70-23-5).

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Computed Properties of C5H7BrO3. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Ethyl 3-bromo-2-oxopropanoate, is researched, Molecular C5H7BrO3, CAS is 70-23-5, about Fe3O4/CuO/ZnO@MWCNT MNCs as an efficient organometallic nanocatalyst promoted synthesis of new 1,2,4-triazolpyrimidoazepine derivatives: Investigation of antioxidant and antimicrobial activity. Author is Shirangi, Hannaneh Sadat; Varasteh Moradi, Ali; Ahmadi Golsefidi, Maziar; Hossaini, Zinatossadat; Jalilian, Hamid Reza.

In this study, the new 1,2,4-triazolpyrimidoazepine derivatives I [R = methoxycarbonyl; R1 = Me, Et; R3 = 4-methoxyphenyl, 4-chlorophenyl, 4-cyanophenyl, etc.; Ar = 4-methoxyphenyl, 4-chlorophenyl] in high yields using multicomponent reactions of isatins, alkyl bromides, activated acetylenic compounds, guanidine, aldehydes and hydrazonoyl chloride in the presence of Fe3O4/CuO/ZnO@MWCNT as a high performance catalyst in water at room temperature was synthesized. The Fe3O4/CuO/ZnO@MWCNT synthesizes using Petasites hybridus rhizome water extract as a green media and moderate base. As well Fe3O4/CuO/ZnO@MWCNT MNCs show a good improvement in the yield of the product and displayed significant reusable activity. Investigation of antioxidant ability of synthesized compounds I using radical trapping of diphenyl-picrylhydrazine (DPPH) and ferric reduction power experiment was another purpose in this research. Also, the antimicrobial activity of some synthesized compounds I proved by employing the disk diffusion test on Gram-pos. and Gram-neg. bacteria. This procedure was some benefits such as short reaction time, product with excellent yields, simple catalyst and products separation

Here is a brief introduction to this compound(70-23-5)Computed Properties of C5H7BrO3, if you want to know about other compounds related to this compound(70-23-5), you can read my other articles.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem