Category: 169048-83-3

Reference of 169048-83-3, Some examples of the diverse research done by chemistry experts include discovery of new medicines and vaccines, improving understanding of environmental issues, and development of new chemical products and materials.169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one, molecular formula is C4H6ClNO2. In a Patent，once mentioned of 169048-83-3

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are potent CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In formula I, A-B is an arylamide moiety.

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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1391NO – PubChem

 

While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards.”Related Products of 169048-83-3

Keywords: Alkylierungen; Aminoalkohole; Epoxidierungen; Peptid-Isostere

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Oxazolidine – Wikipedia,
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Acanthodendrilline (1), a new bromotyrosine alkaloid, was isolated from the Thai marine sponge Acanthodendrilla sp. The structure of 1 was fully characterized by spectroscopic analysis, in agreement with the synthesized compound used to resolve the single chiral center at C-11. Total synthesis of the enantiomers of 1 allowed for the comparison of specific rotation values and hence the determination of the absolute configuration as 11-S. Cytotoxicity evaluation revealed that (S)-1 exhibited approximately three-fold more potent cytotoxicity against the human non-small cell lung cancer H292 cell line than (R)-1.

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Reference of 169048-83-3, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one,introducing its new discovery.

A facile synthesis of novel (R)- and (S)-5-azidomethyl-2-oxazolidinones starting from (S)-epichlorohydrin is described. The (R)-azide was utilized for the preparation of Linezolid.

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Related Products of 169048-83-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one, molecular formula is C4H6ClNO2. In a Article，once mentioned of 169048-83-3

Synthesis of enantiomerically pure 2-((5A)-2-oxo-5-oxazolidinyl) methyl)-1H-isoindole-1,3(2H)-dione, a key precursor in the preparation of oxazolidinone class of antibacterial agents starting from (S)-epichlorohydrin has been achieved.

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Reference：
Oxazolidine – Wikipedia,
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The development of 2-phenylbenzoxazoles as inhibitors of cholesteryl ester transfer protein (CETP) is described. Efforts focused on finding suitable replacements for the central piperidine with the aim of reducing hERG binding: a main liability of our benchmark benzoxazole (1a). Replacement of the piperidine with a cyclohexyl group successfully attenuated hERG binding, but was accompanied by reduced in vivo efficacy. The approach of substituting a piperidine moiety with an oxazolidinone also attenuated hERG binding. Further refinement of this latter scaffold via SAR at the pyridine terminus and methyl branching on the oxazolidinone led to compounds 7e and 7f, which raised HDLc by 33 and 27 mg/dl, respectively, in our transgenic mouse PD model and without the hERG liability of previous series.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of (S)-5-(Chloromethyl)oxazolidin-2-one, you can also check out more blogs about169048-83-3

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Oxazolidine – Wikipedia,
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Chemistry is traditionally divided into organic and inorganic chemistry. SDS of cas: 169048-83-3, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 169048-83-3

(Chemical Equation Presented) Halohydrin dehalogenase from Agrobacterium radiobacter catalyzed the enantioselective ring opening of terminal epoxides with cyanate as a nucleophile, yielding 5-substituted oxazolidinones in high yields and with high enantiopurity (69-98% ee). This is the first example of the biocatalytic conversion of a range of epoxides to the corresponding oxazolidinones.

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Synthetic Route of 169048-83-3, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 169048-83-3, molcular formula is C4H6ClNO2, introducing its new discovery.

Keywords: Alkylierungen; Aminoalkohole; Epoxidierungen; Peptid-Isostere

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 169048-83-3 is helpful to your research. Synthetic Route of 169048-83-3

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Oxazolidine – Wikipedia,
Oxazolidine | C3H1393NO – PubChem

 

Related Products of 169048-83-3, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one,introducing its new discovery.

CETP INHIBITORS DERIVED FROM BENZOXAZOLE ARYLAMIDES

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are potent CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In formula I, A-B is an arylamide moiety.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 169048-83-3, and how the biochemistry of the body works.Related Products of 169048-83-3

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1391NO – PubChem

 

Reference of 169048-83-3, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one, molecular formula is C4H6ClNO2. In a article，once mentioned of 169048-83-3

2-Oxazolidinones are a very interesting class of compounds due to their various pharmacological effects.Two new syntheses of enantiomerically pure (R)- and (S)-5-hydroxymethyl-2-oxazolidinone have been developed starting with D-mannitol, L-ascorbic acid and (R)- or (S)-malic acid. (R)- and (S)-5-hydroxymethyl-2-oxazolidinone have been used to synthesize some new homochiral 2-oxazolidinone derivatives.

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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1395NO – PubChem