Preparation of 2-substituted oxazoline derivative was written by Lu, Zhan; Xi, Tuo; Mei, Yuncai. And the patent was published on May 25,2016.Related Products of 163165-92-2 The following contents are mentioned in the patent:
The invention discloses a method for preparing 2-substituted oxazoline derivative of formula I via reaction of II and III in the presence of palladium catalysts, ligand and a base, wherein R1 is C1-6 alkyl, OH, CN, etc.; R2, R3, and R4 are aryl, C1-6 alkyl, or cycloalkyl; Y is N or C; X halo or halo-like group. The invention provides a route for efficiently and rapidly synthesizing the 2-substituted oxazoline compound, which uses the catalytic amount of palladium and ligand, so that the reaction can be carried out at a high yield and high adaptability, has stereochem. specificity, and can prepare the enantiomer-purity 2-substituted oxazoline compound This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Related Products of 163165-92-2).
(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Related Products of 163165-92-2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem