Aspinall, Helen C. et al. published their research in Dalton Transactions in 2014 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Electric Literature of C11H13NO2

Adding the right (or left) twist to tris-chelate complexes – coordination chemistry of chiral oxazolylphenolates with M3+ ions (M = Al or lanthanide) was written by Aspinall, Helen C.; Bacsa, John; Beckingham, Oliver D.; Eden, Edward G. B.; Greeves, Nicholas; Hobbs, Matthew D.; Potjewyd, Frances; Schmidtmann, Marc; Thomas, Christopher D.. And the article was included in Dalton Transactions in 2014.Electric Literature of C11H13NO2 The following contents are mentioned in the article:

Homoleptic tris-chelate complexes ML3 (M = Al or rare earth; L = chiral or achiral oxazolyl-phenolate or -naphtholate) is reported. In all cases, complexes crystallize as mer-isomers and complete diastereoselectivity is observed on crystallization of the complexes: ML3 crystallize with Λ-helicity at the metal where L = (S)-oxazolylphenolate. Complexes were characterized in solution by NMR spectroscopy, demonstrating rapid ligand exchange at ambient temperature for rare earth complexes, and slow exchange on the NMR timescale for complexes of Al; in all cases the mer-isomer is observed exclusively. Crystal structures are reported for [YL3]2 (L = (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-phenolate), mer-[YbL3] (L = (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-6-methylphenolate) and mer-[AlL3] (L = (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-6-methylphenolate, (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-6-cyanophenolate, (S)-1-(4-isopropyl-4,5-dihydrooxazol-2-yl)naphthalen-2-olate, 1-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)naphthalen-2-olate). This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Electric Literature of C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Electric Literature of C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Djurendic, Evgenija et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2011 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Synthetic Route of C11H13NO2

Synthesis and biological evaluation of 2-oxazoline and salicylic acid derivatives was written by Djurendic, Evgenija; Dojcinovic Vujaskovic, Sanja; Sakac, Marija; Ajdukovic, Jovana; Gakovic, Andrea; Kojic, Vesna; Bogdanovic, Gordana; Klisuric, Olivera; Penov Gasi, Katarina. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2011.Synthetic Route of C11H13NO2 The following contents are mentioned in the article:

Starting from Me salicylate and 2-amino-2-(hydroxymethyl)propane-1,3-diol, or 2-amino-2-methylpropane-1-ol, the 2-oxazoline derivatives of salicylic acid were synthesized. Reactions were performed by microwave irradiation in the presence of tetrabutylammonium bromide or metallic sodium as catalyst, as well as by conventional heating. Microwave-induced reaction of some diols, diamines and amino alcs. with Me salicylate gave mono- and/or bis- derivatives of salicylic acid. The mono- and bis-salicyloyl derivatives were transformed to the corresponding phenyl-azo derivatives The structure of one of the synthesized compound was proved by the X-ray anal. and the R-configuration on its stereocenter was confirmed. The antioxidant and cytotoxic activities of the synthesized derivatives were evaluated in a series of in vitro tests. Some of the compounds e,g., I, exhibited very strong activity against hydroxyl radical. Six tested compounds inhibited growth of MDA-MB-231 cells at a nanomolar concentration Two of the compounds e.g., II, showed high cytotoxicity against MCF7 cells, whereas four of the compounds showed high activity against K562 cells. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Synthetic Route of C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Synthetic Route of C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Schachner, J. A. et al. published their research in Dalton Transactions in 2019 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. In another report, the incorporation of an additional substituted oxazolidine ring over a range of new biphenylazepinium salt organocatalysts for the asymmetric epoxidation of alkenes improved enantiocontrol over the parent structures.Quality Control of 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol

Stereoisomers and functional groups in oxidorhenium(V) complexes: effects on catalytic activity was written by Schachner, J. A.; Berner, B.; Belaj, F.; Moesch-Zanetti, N. C.. And the article was included in Dalton Transactions in 2019.Quality Control of 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:

The syntheses of oxidorhenium(V) complexes [ReOCl(L1a-c)2] (3a-c), equipped with the bidentate, mono-anionic phenol-dimethyloxazoline ligands HL1a-c are described. Ligands HL1b-c contain functional groups on the phenol ring, compared to parent ligand 2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-phenol H1a; namely a methoxy group ortho to the hydroxyl position (2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-6-methoxyphenol, H1b), or a nitro group para to the hydroxyl position (2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-4-nitrophenol, H1c). Furthermore, oxidorhenate(V) complexes (NBu4)[ReOCl3(L1a-b)] (2a-b) were synthesized for solid state structural comparisons to 3a-b. All novel complexes are fully characterized including NMR, IR and UV-Vis spectroscopy, MS spectrometry, X-ray crystallog., elemental anal. as well as cyclic voltammetry. The influence of functional groups (R = -H, -OMe and -NO2) on the catalytic activity of 3a-c was investigated in two benchmark catalytic reactions, namely cyclooctene epoxidation and perchlorate reduction In addition, the previously described oxidorhenium(V) complex [ReOCl(oz)2] (4), employing the phenol-oxazoline ligand 2-(4,5-dihydro-2-oxazolyl)phenol Hoz, was included in these catalysis studies. Complex 4 is a rare case in oxidorhenium(V) chem. where two stereoisomers could be separated and fully characterized. With respect to the position of the oxazoline nitrogen atoms on the rhenium atom, these two stereoisomers are referred to as N,N-cis and N,N-trans isomer. A potential correlation between spectroscopic and structural data to catalytic activity was evaluated. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Quality Control of 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. In another report, the incorporation of an additional substituted oxazolidine ring over a range of new biphenylazepinium salt organocatalysts for the asymmetric epoxidation of alkenes improved enantiocontrol over the parent structures.Quality Control of 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Schachner, Joerg A. et al. published their research in Dalton Transactions in 2020 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Reference of 163165-91-1

Isomers in chlorido and alkoxido-substituted oxidorhenium(V) complexes: effects on catalytic epoxidation activity was written by Schachner, Joerg A.; Belaj, Ferdinand; Moesch-Zanetti, Nadia C.. And the article was included in Dalton Transactions in 2020.Reference of 163165-91-1 The following contents are mentioned in the article:

The syntheses and characterizations of oxidorhenium(V) complexes trans-dichlorido [ReOCl2(PPh3)(L1a)] (trans-2a), cis-dichlorido [ReOCl2(PPh3)(L1b)] (cis-2b) and ethoxido-complex [ReO(OEt)(L1b)2] (4b), ligated with the dimethyloxazoline-phenol ligands HL1a and HL1b are described. The bidentate ligand HL1a (2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)phenol) is unsubstituted on the phenol ring; ligand HL1b (2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-4-nitrophenol) contains a nitro group in para-position to the hydroxy group. In the reaction of precursor complex [ReOCl3(PPh3)2] and HL1a the two stereoisomers cis/trans-2a, with respect to chlorido ligands, are formed. The solid state structures of both isomers cis- and trans-2a were determined by single crystal x-ray diffraction anal. In contrast, with ligand HL1b, only the cis-isomer cis-2b was obtained. Ethoxido-complex 4b is exclusively obtained when precursor [ReOCl3(OPPh3)(SMe2)] is reacted with 2 equiv of HL1b in ethanol in the presence of the base 2,6-dimethylpyridine (lutidine). If no lutidine was added, chlorido-complex [ReOCl(L1b)2] (3b) was obtained. Complexes [ReOCl2(PPh3)(L1a)] (cis/trans-2a), [ReOCl2(PPh3)(L1b)] (cis-2b), [ReO(OMe)(L1a)2] (4a) and [ReO(OEt)(L1b)2] (4b) were tested as homogeneous catalysts in the benchmark reaction of cyclooctene epoxidation The influence of isomerism and effects of ligand substitutions on catalytic activity was studied. Based on the time-conversion plots cis/trans-isomerism does not influence catalytic activity, but electron-withdrawing substituents, as in cis-2b, 3b and 4b, show a beneficial effect. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Reference of 163165-91-1).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Reference of 163165-91-1

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Jia, Wei-Guo et al. published their research in Organometallics in 2018 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Related Products of 163165-91-1

Half-Sandwich Ruthenium Phenolate-Oxazoline Complexes: Experimental and Theoretical Studies in Catalytic Transfer Hydrogenation of Nitroarene was written by Jia, Wei-Guo; Ling, Shuo; Zhang, Hai-Ning; Sheng, En-Hong; Lee, Richmond. And the article was included in Organometallics on January 8,2018.Related Products of 163165-91-1 The following contents are mentioned in the article:

Five Ru complexes [Ru(p-cymene)LCl] containing phenolate-oxazoline ligands [LH = 2-(4,5-dihydrooxazol-2-yl)phenol (1), 2-(4-methyl-4,5-dihydrooxazol-2-yl)phenol (2); L = 2-(4-ethyl-4,5-dihydrooxazol-2-yl)phenol (3), 2-(4-phenyl-4,5-dihydrooxazol-2-yl)phenol (4), 2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)phenol (5)] were synthesized and characterized. The solid-state structures of all Ru complexes were determined by single-crystal x-ray diffraction. The catalytic activities of these complexes in the transfer hydrogenation reaction of nitroarenes to anilines were studied. Aniline and their derivatives were obtained in good to excellent yields with iso-PrOH as the hydride source. The present protocol provides an environmentally benign synthetic method for the reduction of nitroarenes to anilines without employing harsh reaction conditions. Theor. studies employing d. functional theory were carried with the aim to propose a feasible reaction mechanism and to draw insights into the reactivity of the half-sandwich Ru catalyst. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Related Products of 163165-91-1).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Related Products of 163165-91-1

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Liu, Jinyong et al. published their research in Inorganic Chemistry in 2017 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Category: oxazolidine

Ligand Design for Isomer-Selective Oxorhenium(V) Complex Synthesis was written by Liu, Jinyong; Su, Xiaoge; Han, Mengwei; Wu, Dimao; Gray, Danielle L.; Shapley, John R.; Werth, Charles J.; Strathmann, Timothy J.. And the article was included in Inorganic Chemistry on February 6,2017.Category: oxazolidine The following contents are mentioned in the article:

Recently, N,N-trans Re(O)(LN-O)2X (LN-O = monoanionic N-O chelates; X = Cl or Br prior to being replaced by solvents or alkoxides) complexes are superior to the corresponding N,N-cis isomers in the catalytic reduction of perchlorate via oxygen atom transfer. However, reported methods for Re(O)(LN-O)2X synthesis often yield only the N,N-cis complex or a mixture of trans and cis isomers. This study reports a geometry-inspired ligand design rationale that selectively yields N,N-trans Re(O)(LN-O)2Cl complexes. Anal. of the crystal structures revealed that the dihedral angles (DAs) between the two LN-O ligands of N,N-cis Re(O)(LN-O)2Cl complexes are <90°, whereas the DAs in most N,N-trans complexes are >90°. Variably sized alkyl groups (-Me, -CH2Ph, and -CH2Cy) were then introduced to the 2-(2′-hydroxyphenyl)-2-oxazoline (Hhoz) ligand to increase steric hindrance in the N,N-cis structure, and substituents as small as -Me completely eliminate the formation of N,N-cis isomers. The generality of the relation between N,N-trans/cis isomerism and DAs is further established from a literature survey of 56 crystal structures of Re(O)(LN-O)2X, Re(O)(LO-N-N-O)X, and Tc(O)(LN-O)2X congeners. D. functional theory calculations support the general strategy of introducing ligand steric hindrance to favor synthesis of N,N-trans Re(O)(LN-O)2X and Tc(O)(LN-O)2X complexes. This study demonstrates the promise of applying rational ligand design for isomeric control of metal complex structures, providing a path forward for innovations in a number of catalytic, environmental, and biomedical applications. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Category: oxazolidine).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Category: oxazolidine

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Berg, David J. et al. published their research in Canadian Journal of Chemistry in 2005 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.HPLC of Formula: 163165-91-1

Lanthanide complexes of an oxazoline-phenoxide hybrid chelate was written by Berg, David J.; Zhou, Chuanjian; Barclay, Tosha; Fei, Xuening; Feng, Shengyu; Ogilvie, Kevin A.; Gossage, Robert A.; Twamley, Brendan; Wood, Mark. And the article was included in Canadian Journal of Chemistry on May 31,2005.HPLC of Formula: 163165-91-1 The following contents are mentioned in the article:

The synthesis of 2-(2′-hydroxy-3′-allylphenyl)-4,4-dimethyl-2-oxazoline, H-Allox (3), and lanthanide tris chelate complexes, mer-Ln(Allox)3 (Ln = La (4), Ce (5), Sm (6), Er (7), and Y (8)), derived from it are reported. A six-coordinate mer geometry without alkene coordination was confirmed in the solid state by x-ray crystallog. for 5 and 7. Variable-temperature NMR experiments suggested that this is the most stable isomer in solution as well, although the inequivalent ligand environments undergo rapid averaging at room temperature for all five complexes. A mechanistic study indicated that this fluxional process is an intramol. six-coordinate rearrangement, but it was not possible to distinguish between a Bailar (trigonal) or Ray-Dutt (rhombic) twist. Kinetic parameters for the fluxional process were determined by line shape anal. for 8 yielding ΔH‡ = 24 ± 2 kJ mol-1 and ΔS‡ = -99 ± 10 J mol-1 K-1. The structural and dynamic features of 4-8 were compared with the related In, Ga, and Al tris(2-oxazolylphenoxides). This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1HPLC of Formula: 163165-91-1).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.HPLC of Formula: 163165-91-1

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Mugesh, Govindasamy et al. published their research in European Journal of Inorganic Chemistry in 2001 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Formula: C11H13NO2

2-(4′,4′-Dimethyl-3′,4′-dihydrooxazol-2′-yl)phenol: some first-row transition metal complexes of this naturally occurring binding group was written by Mugesh, Govindasamy; Singh, Harkesh B.; Butcher, Ray J.. And the article was included in European Journal of Inorganic Chemistry on March 31,2001.Formula: C11H13NO2 The following contents are mentioned in the article:

The synthesis and characterization of monomeric MnIII, CoII, NiII, CuII, and ZnII phenolates derived from a biol. relevant ligand, 2-(4′,4′-dimethyl-3′,4′-dihydrooxazol-2′-yl)phenol (1), are described. The addition of Mn(OAc)2·4H2O to an EtOH solution of 1 affords an unexpected 1:3 [Mn(OR){O(Ox)}2] (2) [R = o-C6H4CONHC(Me2)CH2OH, Ox = 2-(4,4-dimethyl-2-oxazolinyl)phenyl] in which one of the five-membered oxazoline rings is partially hydrolyzed. [M{O(Ox)}2] [M = Co (3), Ni (4), Cu (6), or Zn (7)] were prepared in good yield by the reactions of 1 with the corresponding metal acetates. Novel formation of the six-coordinate NiII complex (Ni{O(Ox)}2(OAc)2, 5) with neutral HOAc was observed during the crystallization process. The complexes were characterized by elemental anal., magnetic susceptibility, as well as EPR, 1H NMR, electronic, and mass spectral techniques. 2, 3, 5, 6, And 7 were characterized by single crystal x-ray diffraction studies. 2 Is six-coordinate whereas 3, 6, and 7 are four-coordinate with two bidentate oxazoline ligands. The geometry around the metal center is distorted tetrahedral for all of the four-coordinate complexes. Complex 5 is octahedral with four coordination sites occupied by the two bidentate oxazoline ligands and the other two are occupied by two neutral HOAc mols. The hydroxy groups of the coordinated HOAc are H-bonded to the phenolate O atoms of the oxazoline ligands. The variable-temperature 1H NMR spectroscopic studies of 7 indicate that the interconversion between the (M) and (P) helix is slow at low temperatures This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Formula: C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Formula: C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Clarke, David S. et al. published their research in Synthetic Communications in 1996 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol

A facile one stage synthesis of oxazolines under microwave irradiation was written by Clarke, David S.; Wood, Robin. And the article was included in Synthetic Communications on April 30,1996.Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:

A rapid, high yielding procedure for the synthesis of 2-substituted oxazolines I (R = Ph, 4-pyridyl, CH2CH2CH2Ph, etc.), has been achieved under microwave irradiation from alkyl and aryl nitriles RCN and H2NCMe2CH2OH using a mild Lewis acid catalyst. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

 

Ghoshal, Shamik et al. published their research in Journal of Chemical Research in 2007 | CAS: 163165-91-1

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Category: oxazolidine

Synthesis and characterization of dialkyl[2-(2-phenolato)oxazolines] of gallium(III) and indium(III): crystal structure of [{InMe2(OC6H4-OxMe2)}2] was written by Ghoshal, Shamik; Wadawale, Amey; Jain, Vimal K.; Nethaji, Munirathinam. And the article was included in Journal of Chemical Research on April 30,2007.Category: oxazolidine The following contents are mentioned in the article:

Reactions of trialkylgallium and -indium etherates with 2-(2-hydroxyphenyl)oxazolines afforded colorless dialkyl[2-(2-phenolato)oxazoline]gallium and -indium complexes I and II (R = Me or Et; Ox = oxazoline, R’ = Me or Et; R” = Me or H). These complexes were characterized by elemental anal., IR, mass and NMR (1H and 13C) spectral data. [{InMe2(OC6H4-OxMe2)}2] has a dimeric structure as established by x-ray diffraction. The In atom acquires an irregular trigonal bipyramidal geometry defined by C2O2N ligating atoms. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Category: oxazolidine).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Category: oxazolidine

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1