Visible light photocatalytic asymmetric synthesis of pyrrolo[1,2-a]indoles via intermolecular [3+2] cycloaddition was written by Casado-Sanchez, Antonio;Domingo-Legarda, Pablo;Cabrera, Silvia;Aleman, Jose. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Safety of (S)-4-Phenyloxazolidin-2-one This article mentions the following:
The intermol. diastereoselective and enantioselective synthesis of pyrrolo[1,2-a]indoles is developed through a [3 + 2] cycloaddition between silyl-indole derivatives and α,β-unsaturated N-acyl oxazolidinones by merging photocatalysis and Lewis acid catalysis. In the experiment, the researchers used many compounds, for example, (S)-4-Phenyloxazolidin-2-one (cas: 99395-88-7Safety of (S)-4-Phenyloxazolidin-2-one).
(S)-4-Phenyloxazolidin-2-one (cas: 99395-88-7) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Safety of (S)-4-Phenyloxazolidin-2-one
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem