Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Kang, Wu, once mentioned the application of 99395-88-7, Name is (S)-4-Phenyloxazolidin-2-one, molecular formula is C9H9NO2, molecular weight is 163.1733, MDL number is MFCD00043396, category is oxazolidines. Now introduce a scientific discovery about this category, Category: oxazolidines.
A simple oxazolidine linker for solid-phase synthesis of peptide aldehydes
A very simple and cheap linker has been used for solid-phase synthesis of peptide aldehydes. Protected amino acid aldehydes are immobilized on 2-Cl(trt) resin as oxazolidine formation via diethanolamine. After classical Fmoc SPPS, treatment of the resin with AcOH/DCM/H2O (8:1:1) affords peptide aldehydes in high yield and purity. (C) 2011 Elsevier Ltd. All rights reserved.
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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem