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Bicyclo[3,1,0]hexane containing oxazolidinone antibioytics and derivatives thereof
Oxazolidinones having a bicyclic[3.1.0] hexane containing moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, streptococci and enterococci, Bacteroides spp., Clostridia spp. species, as well as acid-fast organisms such as Mycobacterium tuberculosis and other mycobacterial species. The compounds are represented by structural formula I: 1its enantiomer, diastereomer, or pharmaceutically acceptable salt or ester thereof, and wherein the variables R1, R2, R3, R4, R4a, A, Ar, HAr, n, r, and s are as defined herein.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: 5-(Hydroxymethyl)oxazolidin-2-one, you can also check out more blogs about7517-99-9
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1300NO – PubChem