Reference of 169048-83-3, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one, molecular formula is C4H6ClNO2. In a article£¬once mentioned of 169048-83-3
Electrogenerated chiral 4-methoxy-2-oxazolidinones as diastereoselective amidoalkylation reagents for the synthesis of beta-amino alcohol precursors
A flexible and efficient synthesis of enantiomerically pure 4,5-substituted 2-oxazolidinones – important target molecules as precursors of pharmacologically active 2-oxazolidinones, beta-amino alcohols, beta-blockers and azasugar derivatives – is described. As starting materials, the enantiopure storage forms of chiral N-acyliminium ions (4RS,5S)-5-chloromethyl-4-methoxy-1,3-oxazolidin-2-one (2) and (4RS,5R)-4-methoxy-5-methyl-1,3-oxazolidin-2-one (3) were used; these are readily available from the chiral pool with the aid of electrochemical transformations. Substitution of the 4-methoxy group in building blocks 2 and 3 with a large variety of organometallic nucleophiles resulted in the trans-diastereoselective formation of enantiopure 4,5-disubstituted 2-oxazolidinones, with a high degree of flexibility in the substituent at the 4-position.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 169048-83-3
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1401NO – PubChem