Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: (R)-4-Benzyl-3-(3-methylbutanoyl)oxazolidin-2-one, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 145589-03-3
Discovery of a new class of ghrelin receptor antagonists
A series of benzodiazepine antagonists of the human ghrelin receptor GHSR1a were synthesized and their antagonism and metabolic stability were evaluated. The potency of these analogs was determined using a functional aequorin (Euroscreen) luminescent assay measuring the intracellular Ca2+ concentration, and their metabolic stability was measured using an in vitro rat and human S9 hepatocyte assay. These efforts led to the discovery of a potent ghrelin antagonist with good rat pharmacokinetic properties.
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Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H2605NO – PubChem