875444-08-9, (4S,5R)-5-(3,5-Bis(trifluoromethyl)phenyl)-4-methyloxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 5: (4S,5R)-5-(3,5-Bis-trifluoromethyl-phenyl)-3-(2-bromo-5-tri?uoromethyl-benzyl)-4- niethyl-oxazolidin-2-one[00524] To (4S,5R)-5-(3,5-bis-t?fluoromethyl-phenyl)-4-methyl-oxazohdin-2-one (0246g,0 79mmol) in THF (1OmL) at room temperature was added sodium hexamethyldisilazane (IM inTHF, 1 02mL, 1 02mmol), and the reaction was stirred for 15 minutes 2-Bromo-5-(tnfluoromethyl)benzyl bromide (025Og, 0 79mmol) was added, and the reaction was stirred overnight at room temperature The mixture was worked-up with EtOAc and H2O, and the crude material was purified by silica gel chromatography to give the title compound
The synthetic route of 875444-08-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; AMIRA PHARMACEUTICALS, INC.; WO2009/108720; (2009); A2;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem