Brief introduction of 695-53-4

The synthetic route of 695-53-4 has been constantly updated, and we look forward to future research findings.

695-53-4, 5,5-Dimethyloxazolidine-2,4-dione is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,695-53-4

Example 124(3R*,4R*)-N-[3,5-bis(trifluoromethyl)benzyl]-1-[2-(5,5-dimethyl-2,4-dioxo-1,3-oxazolidin-3-yl)ethyl]-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide monohydrochloride(step 1)To a solution of 5,5-dimethyl-1,3-oxazolidine-2,4-dione (500 mg) in DMF (10 mL) was added NaH (186 mg) at room temperature, and the mixture was stirred for 5 min. 1-Bromo-2-chloroethane (430 muL) was further added, and the mixture was stirred at room temperature for 4 days. The reaction mixture was concentrated under reduced pressure, and ethyl acetate was added to the residue. The organic layer was washed with aqueous citric acid solution and water and dried, and the solvent was evaporated under reduced pressure to give crude 3-(2-chloroethyl)-5,5-dimethyl-1,3-oxazolidine-2,4-dione as a colorless oil.

The synthetic route of 695-53-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Shirai, Junya; Morimoto, Shinji; Sugiyama, Hideyuki; Sakauchi, Nobuki; Yoshikawa, Takeshi; US2008/275085; (2008); A1;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem