497-25-6, Oxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a 25ml Schlenk reaction tube was added 1.0mmol (87 ¡¤ 1mg) oxazolidin-2-one, 0. 05mmol(11.2 mg) of palladium acetate, 0.001 mmol (1.7 mg) of H5PMo10V2O40, 0.05 mmol (5.6 mg) of 1,4-hydroquinone, 0.1 mmol(8.2 mg) of NaOAc followed by 1 mL of N, N-dimethylformamide solvent and then measuring 2.0 mmo 1 (236 mg) of 4-methylstyrene with a pipette in an oil bath at 60 C. 24 hours, after the reaction, the resulting product using a simple column chromatography device,The product was eluted with dichloromethane and then three times with distilled water, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated by rotary evaporationThe crude product was reduced. The crude product was isolated by column (200-300 mesh silica gel) using petroleum ether and ethyl acetate as eluant (5: 1) to give 150.2 mg of 3- (1- (4-methylphenyl) vinyl) oxazolidin-2-one having a purity of more than 99%. Isolated yield 74%.
The synthetic route of 497-25-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Fujian Normal University; Huang Qiufeng; Qiu Lin; Ke Shaojia; Zhang Xiaofeng; Lin Shen; (12 pag.)CN104230835; (2017); B;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem