497-25-6, Oxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A 5 mL round bottom flask was successively charged with the two nucleophiles (1.0 mmol-10.0 mmol), the alkynylcopper reagent (0.5 mmol) and the solvent (1 mL). The resulting bright yellow slurry was then treated with the ligand (0.5 mmol if bidentate and 1.0 mmol if monodentate) and the reaction mixture was stirred at 25 C for 16h and at 375 rpm and under an atmosphere of oxygen (balloon). The reaction was then diluted with 15 mL of an aqueous mixture of saturated ammonium chloride and 25 % ammonium hydroxide (1:1 solution) and extracted with 3¡Á10 mL of ethyl acetate. Combined organic layers were washed with 10 mL of water and 10 mL of brine, dried over MgSO4 and concentrated to dryness. Nitrocyclohexane (65 muL, 0.5 mmol) and chromium(III) acetylacetonate (27 mg, 75mumol) were added to the crude and it was dissolved in 1 mL of CDCl3.
The synthetic route of 497-25-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Guissart, Celine; Luhmer, Michel; Evano, Gwilherm; Tetrahedron; vol. 74; 47; (2018); p. 6727 – 6736;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem