Brief introduction of 169048-83-3

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Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of (S)-5-(Chloromethyl)oxazolidin-2-one, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 169048-83-3

A three-step synthesis of optically active 5-halomethyl-2-oxazolidinones; asymmetric desymmetrization of prochiral 1,3-dihalo-2-propyl carbamates

Optically active 5-bromomethyl-2-oxazolidinones (2a and 3a) and 5-chloromethyl-2-oxazolidinones (2b and 3b) were readily prepared from prochiral 1,3-dibromo-2-propanol (7a) and 1,3-dichloro-2-propanol (7b) by a three-step sequence involving formation of carbamates (6a-c) followed by asymmetric desymmetrization (up to 50% de) and debenzylation by anisole-methanesulfonic acid system.

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Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1404NO – PubChem