184346-45-0, Name is (S)-4-Isopropyl-5,5-diphenyloxazolidin-2-one, belongs to oxazolidine compound, is a common compound. Electric Literature of 184346-45-0In an article, once mentioned the new application about 184346-45-0.
A range of chiral ester and chiral imide derivatives of 2-oxocyclohexanecarboxylic acid were utilised in double-Mannich reactions with bis(aminol)ethers to develop an asymmetric synthesis of azabicyclo[3.3.1]nonanes. An improved method for the double-Mannich reaction of beta-ketoesters and bis(aminol)ethers using sub-stoichiometric quantities of a Lewis acid was developed. Additionally, a sequential, double-Mannich approach was investigated incorporating chiral auxiliaries into N,O-acetals. The use of oxazolidinone auxiliaries afforded the best yields and diastereoselectivities enabling separation of the resulting diastereomers of the azabicyclo[3.3.1]nonanes.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Electric Literature of 184346-45-0, you can also check out more blogs about184346-45-0
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2651NO – PubChem