Awesome Chemistry Experiments For (R)-Methyl 2-oxooxazolidine-4-carboxylate

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144542-43-8, Name is (R)-Methyl 2-oxooxazolidine-4-carboxylate, belongs to oxazolidine compound, is a common compound. SDS of cas: 144542-43-8In an article, once mentioned the new application about 144542-43-8.

(Figure presented) 4-Hydroxy-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl esters, which are readily prepared from serine and terminal acetylenes, undergo Claisen rearrangement to piperidine derivatives when heated with butyl vinyl ether in the presence of Hg(OAc)2 and Et3N. This route to optically pure piperidines having substituents alpha to nitrogen is general, and the rearrangement products are versatile intermediates for making a broad range of amines containing a substituted piperidine subunit.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1463NO – PubChem