Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. COA of Formula: C10H11NO2. Introducing a new discovery about 102029-44-7, Name is (R)-4-Benzyl-2-oxazolidinone
A collective synthesis of 4-hydroxy-2-pyridone alkaloids – specifically, pretenellin B, prebassianin B, farinosone A, militarione D, pyridovericin, and torrubiellone C – has been achieved. Key steps include using a strategic convergent method to synthesize the densely substituted pyridone key intermediate by Suzuki-Miyaura cross-coupling reaction, a divergent synthesis approach of target molecules by aldol condensation of pyridone intermediate with homologous aldehydes, and an iterative synthesis of homologous aldehydes with all-trans-polyene backbones. Interestingly, among the six tumor cell lines investigated, torrubiellone C was found to induce potent and apoptotic inhibitory activities on Jurkat T cells with IC50 values of 7.05 muM. Hence, this approach could potentially contribute to the synthesis of bioactive small-molecule libraries as well as drug discovery.
I am very proud of our efforts over the past few months and hope to 102029-44-7 help many people in the next few years. COA of Formula: C10H11NO2
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1800NO – PubChem