Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of Heterocyclic Chemistry called Green Synthesis of Imidazole Derivatives using Fe3O4-MNPs as Reusable Catalyst, Author is Shafaei, Faezeh; Sharafian, Shirin, which mentions a compound: 70-23-5, SMILESS is O=C(OCC)C(CBr)=O, Molecular C5H7BrO3, Reference of Ethyl 3-bromo-2-oxopropanoate.
In this research, a one-pot, efficient, and high yielding procedure for the synthesis of imidazole derivatives I (R = H, Me; R1 = tert-Bu, Ph, 4-BrC6H4, etc.; R2 = COOEt, 4-MeOC6H4, 4-O2NC6H4) is investigated. The procedure was carried out via multicomponent reaction of isothiocyanate, alkyl bromides, N-methylimidazole, and triphenylphosphine in the presence of magnetic iron oxide nanoparticles (Fe3O4-MNPs) as reusable catalyst under solvent-free conditions at 50°. Also, Fe3O4-MNPs were produced using green synthetic method by reduction of ferric chloride solution with Clover Leaf water extract The nanoparticles generated using this procedure can potentially be important in different purposes such as organic synthesis. These procedures have some advantages such as easy separation of products, green conditions, and reusability and easy separation of catalyst.
This literature about this compound(70-23-5)Reference of Ethyl 3-bromo-2-oxopropanoatehas given us a lot of inspiration, and I hope that the research on this compound(Ethyl 3-bromo-2-oxopropanoate) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem