In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 16251-45-9, name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, introducing its new discovery. Synthetic Route of 16251-45-9
The reaction of beta-amino alcohols with 1,1?carbonyldiimidazole in dichloromethane is affected by the size of the nitrogen substituent. 1,3-Oxazolidin-2-ones are exclusively obtained from N-H, N-methyl and N-arylmethyl derivatives. O-(1-Imidazolyl)carbonyl derivatives are formed as intermediates from N-[1-(2-pyridyl)alkyl]-(S)-valinol and are mainly or exclusively converted into aziridines in the presence of water, although the cyclization is impeded by large N-substituents such as triphenylmethyl.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 16251-45-9 is helpful to your research. Synthetic Route of 16251-45-9
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2154NO – PubChem