Application of 39657-45-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.39657-45-9, Name is Isoxazolidine hydrochloride, molecular formula is C3H8ClNO. In a article£¬once mentioned of 39657-45-9
The alpha-effect in cyclic secondary amines: new scaffolds for iminium ion accelerated transformations
Five-membered secondary amine heterocycles containing an alpha-heteroatom were prepared and shown to be ineffective as catalysts for the iminium ion catalysed Diels-Alder reaction between cinnamaldehyde and cyclopentadiene. Their six-membered counterparts proved to be highly active catalysts. In stark contrast, the catalytic activity observed when comparing the non alpha-heteroatom cyclic amines proline methyl ester and methyl pipecolinate showed the five-membered ring amine was significantly more active. Concurrent density functional theoretical calculations suggest a rationale for the observed trends in reactivity, highlighting that LUMO activation through an iminium ion intermediate plays a key role in catalytic activity.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 39657-45-9
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1279NO – PubChem