Allali, Hocine’s team published research in Tetrahedron: Asymmetry in 2004-04-19 | CAS: 4042-43-7

Tetrahedron: Asymmetry published new progress about Hofmann degradation. 4042-43-7 belongs to class oxazolidine, name is (R)-4-Methyloxazolidin-2-one, and the molecular formula is C4H7NO2, SDS of cas: 4042-43-7.

Allali, Hocine published the artcileAn easy route to 4-substituted 2-oxazolidinones from prochiral 1,3-diols, SDS of cas: 4042-43-7, the main research area is acetoxy amide Hofmann rearrangement; oxazolidinone asym preparation.

A synthesis of 4-substituted 2-oxazolidinones I (R = Me, t-BuOCH2), starting from prochiral 1,3-diols, has been developed. After enzymic desymmetrization the resulting monoacetylated diols were transformed into amides. A Hofmann rearrangement of these amides gave I in good yields and enantiomeric excess.

Tetrahedron: Asymmetry published new progress about Hofmann degradation. 4042-43-7 belongs to class oxazolidine, name is (R)-4-Methyloxazolidin-2-one, and the molecular formula is C4H7NO2, SDS of cas: 4042-43-7.

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem