Computed Properties of C5H2Cl2N4. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2,6-Dichloropurine, is researched, Molecular C5H2Cl2N4, CAS is 5451-40-1, about An efficient regioselective synthesis of N-alkylated purine-triazole analogues. Author is Pandit, Chintan; Pandya, Mayank; Jadeja, Yashwantsinh; Gohel, Jyoti; Kapadiy, Khushal.
Nitrogen rich purine adduct 6-chloro-2-hydrazinyl-9H-purine was prepared by reaction of 2,6-dichloro purine with hydrazine hydrate and converted to 4-chloro-8-(3-phenoxyphenyl)-1H,5aH,6H-[1,2,4]triazolo[3,4-b]purine by a simple cyclization process (con.HCl & methanol) on reaction with 3-phenoxy benzaldehyde. These studies gave an idea regarding replacement of chlorine out of C-2 or C-6 position. Novelty was introduced by alkyl substation at N-9 position of imidazole ring and at -NH of triazole ring and a series of 4-chloro-5a,6-dihydro-1,6-dialkylated-8-(3-phenoxyphenyl)-1H-[1,2,4]triazolo[3,4-e]purine I [R = CH3, (CH2)2CH3, CH(CH3)2, etc.] hybrids were synthesized.
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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem