Synthetic Route of 189028-93-1, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 189028-93-1, Name is (S)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione, molecular formula is C20H18FNO4. In a Patent，once mentioned of 189028-93-1
A process for the preparation of intermediates according to Mai Bu (by machine translation)
The invention discloses a method for the preparation of intermediates according to Mai Bu, the intermediate body is (S) – 1 – (4-fluoro phenyl) – 5 – (2-oxo-4-phenyl-oxazolidine-3-yl) pentane -1,5-diketone, by 1 – (4-fluoro phenyl) ethanone and silane protective agent reaction generating ((1 – (4-fluoro phenyl) vinyl) oxygen) trimethyl silane, in addition acryloyl chloride and (S) – 4-phenyl-oxazolidine-2-ketone reaction condensation to obtain (S) – 3-acryloyl-4-phenyl-oxazolidine-2-one, then the ((1 – (4-fluoro phenyl) vinyl) oxygen) trimethyl silane and (S) – 3-acryloyl-4-phenyl-oxazolidine-2-one obtained through the condensation reaction. The process route is the route convergence devices, to achieve the overall yield of 80% or more, process the raw materials is cheap and easy to obtain, with the solvent, low toxicity, production cycle is short, the production cost is cheap, simple operation the production unit, safety and environmental protection, is very suitable for industrial production. (by machine translation)
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 189028-93-1. In my other articles, you can also check out more blogs about 189028-93-1
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2812NO – PubChem