A new application about Oxazolidin-2-one

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497-25-6, Name is Oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. HPLC of Formula: C3H5NO2In an article, once mentioned the new application about 497-25-6.

A series of Nalpha-benzyloxycarbonyl- and Nalpha-acyl-L-leucine(2-phenylaminoethyl)amide derivatives were prepared and evaluated for their inhibitory activity against rabbit and human cysteine proteases cathepsins K, L, and S. These data indicate that Nalpha-acyl-alpha-amino acid-(arylaminoethyl)amides represent a new class of selective non-covalent inhibitors of cathepsin K. Compounds 4b, 4e, and 4g exhibit high potency toward rabbit and human cathepsin K (IC50 < 0.006 muM) and are characterized by an excellent selectivity profile vs human cathepsins L and S. Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 497-25-6 Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H293NO – PubChem