A new application about 5-(Chloromethyl)oxazolidin-2-one

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Copper-catalyzed oxidative cross-coupling of H-phosphonates and amides to N-acylphosphoramidates

A simple combination of copper(II) acetate (Cu(OAc)2) and an appropriate base could promote oxidative cross-coupling of H-phosphonates and amides using air as a terminal oxidant. The substrate scope was broad with respect to both dialkyl H-phosphonates and nitrogen nucleophiles (including oxazolidinone, lactam, pyrrolidinone, urea, indole, and sulfonamide derivatives), giving the corresponding P-N coupling products in moderate to high yields.

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Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1441NO – PubChem