Ryono, Denis E. et al. published their patent in 2011 |CAS: 97859-49-9

The Article related to phosphonate phosphinate pyrazolylamide glucokinase activator preparation, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Computed Properties of 97859-49-9

On March 22, 2011, Ryono, Denis E.; Cheng, Peter T. W.; Bolton, Scott A.; Chen, Sean; Shi, Yan; Meng, Wei; Tino, Joseph A. published a patent.Computed Properties of 97859-49-9 The title of the patent was Preparation of phosphonate and phosphinate pyrazolylamide glucokinase activators. And the patent contained the following:

Pyrazoloamides are provided which are phosphonate and phosphinate glucokinase activators that are useful in treating diabetes and related diseases and have the structure I (circle = pyrazoyl ring; R4 = -(CH2)n-Z-(CH2)m-PO(OR7)(OR8), -(CH2)nZ-(CH2)m-PO(OR7)R9, or -(CH2)nZ-(CH2)m-PO(R9)(R10); R5 and R6 are independently selected from H, alkyl and halogen; Y is R3(CH2)s, wherein R3 is aryl , s is 0, X is a bond; and n, Z, m, R4, R5, R6, and R7 are as defined herein; or a pharmaceutically acceptable salt thereof). The experimental process involved the reaction of (R)-5-(Hydroxymethyl)oxazolidin-2-one(cas: 97859-49-9).Computed Properties of 97859-49-9

The Article related to phosphonate phosphinate pyrazolylamide glucokinase activator preparation, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Computed Properties of 97859-49-9

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem