On November 30, 2009, Concellon, Carmen; Duguet, Nicolas; Smith, Andrew D. published an article.Reference of (S)-4-Isopropyl-5,5-dimethyloxazolidin-2-one The title of the article was N-Heterocyclic Carbene-Mediated Enantioselective Addition of Phenols to Unsymmetrical Alkylarylketenes. And the article contained the following:
Chiral N-heterocyclic carbenes (NHCs) mediate the enantioselective addition of 2-phenylphenol to unsym. alkylarylketenes, delivering α-alkyl-α-arylacetic acid derivatives with good levels of enantiocontrol (up to 84% ee). Enantiodivergent stereochem. outcomes are observed using 2-phenylphenol and benzhydrol in the NHC-promoted esterification reaction using a triazolium precatalyst derived from pyroglutamic acid, consistent with distinct mechanistic pathways operating within these processes. The experimental process involved the reaction of (S)-4-Isopropyl-5,5-dimethyloxazolidin-2-one(cas: 168297-86-7).Reference of (S)-4-Isopropyl-5,5-dimethyloxazolidin-2-one
The Article related to addition stereoselective phenol alkylarylketene n heterocyclic carbene catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.Reference of (S)-4-Isopropyl-5,5-dimethyloxazolidin-2-one
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem