On July 3, 2014, Yang, Yushe; Guo, Bin; Li, Zhan; Li, Wei published a patent.Synthetic Route of 97859-49-9 The title of the patent was Benzoxazine-oxazolidinone compounds as antiinfective agents and their preparation, pharmaceutical compositions and use in the treatment of multidrug resistant bacterial infections. And the patent contained the following:
Disclosed are benzoxazine-oxazolidinone compounds of formula I and their optical isomers, pharmaceutically acceptable salts, preparation method and application in preparing drugs for treating an infectious disease and in particular, an infectious disease caused by multidrug resistant bacteria. Compounds of formula I wherein R1 is amino and derivatives, phosphonate, succinate, L-arginine; R2 is (un)branched alkyl; R3 is halo, CN, OH, amino and derivatives, etc.; and their optical isomers, pharmaceutically acceptable salts thereof, are claimed. Compounds of formula I were prepared by using cross-coupling as the key steps. All the invention compounds were evaluated for their antibacterial activity. The experimental process involved the reaction of (R)-5-(Hydroxymethyl)oxazolidin-2-one(cas: 97859-49-9).Synthetic Route of 97859-49-9
The Article related to benzoxazine oxazolidinone preparation antiinfective treatment multidrug resistant bacterial infection, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Synthetic Route of 97859-49-9
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem