Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 151509-01-2, is researched, SMILESS is O=C(OC)C1=C(CN)N=CC=C1.[H]Cl, Molecular C8H11ClN2O2Journal, Journal of Heterocyclic Chemistry called Synthesis of a new 1,4-dihydropyridine containing the imidazo[1,5-a]pyridine nucleus, Author is Fos, Empar; Bosca, Francisco; Mauleon, David; Carganico, Germano, the main research direction is imidazopyridinyl dihydropyridine preparation calcium channel blocker; antithrombotic imidazopyridinyl dihydropyridine preparation; pyridine imidazopyridinyl preparation; nifedipine imidazopyridinyl analog preparation.Electric Literature of C8H11ClN2O2.
The preparation of the new dihydropyridine di-Et 1,4-dihydro-4-(imidazo[1,5-a]pyridin-8-yl)-2,6-dimethylpyridine-3,5-dicarboxylate (I) is described. After many attempts to prepare the key intermediate aldehyde II by different approaches, this compound was obtained in good yields from Me 2-cyano-3-pyridinecarboxylate. A 3-step procedure involving reduction to the amine, formylation with concomitant cyclization and reduction of the ester group was used. I had activity as calcium antagonist but it was devoid of activity as thromboxane inhibitor.
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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem