Reference of 6-Hydroxy-2-methylpyrimidin-4(3H)-one. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one, is researched, Molecular C5H6N2O2, CAS is 1194-22-5, about On the Synthesis of 1,1-Diamino-2,2-dinitroethene (FOX-7) by Nitration of 4,6-Dihydroxy-2-methylpyrimidine. Author is Latypov, Nikolaj V.; Johansson, Martin; Holmgren, Erik; Sizova, Ekaterina V.; Sizov, Vladimir V.; Bellamy, Anthony J..
The synthesis of 1,1-diamino-2,2-dinitroethene (FOX-7) by nitration of 4,6-dihydroxy-2-methylpyrimidine and hydrolysis of the resulting intermediate 2-dinitromethylene-5,5-dinitropyrimidine-4,6-dione was studied. By varying the reaction parameters the optimal conditions for the synthesis of FOX-7 were identified and gave a >90% yield of the pure product. The optimized process allowed the spent acid to be recycled without loss of yield, with almost stoichiometric consumption of HNO3. The purity of the FOX-7 was determined by using a newly developed HPLC method.
There is still a lot of research devoted to this compound(SMILES：CC1=NC(=CC(N1)=O)O)Reference of 6-Hydroxy-2-methylpyrimidin-4(3H)-one, and with the development of science, more effects of this compound(1194-22-5) can be discovered.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem