Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2,6-Dichloropurine, is researched, Molecular C5H2Cl2N4, CAS is 5451-40-1, about Green Regioselective Synthesis of (Purin-6-yl)hydrazones.COA of Formula: C5H2Cl2N4.
Some unique purine hydrazinylidene derivatives I (R1 = Me, CN, CF3; R2 = H, Me, F; R3 = OMe, OEt, pyrazin-2-yl) were synthesized by the regioselective reaction of 2,6-dichloropurine with hydrazine hydrate, followed by condensation with com. available 1,3-dicarbonyl compounds according to a green chem. approach. The regioselectivity of chlorine substitution in 2,6-dichloropurine was established by HMBC (Heteronuclear Multiple Bond Correlation) NMR technique.
Here is just a brief introduction to this compound(5451-40-1)COA of Formula: C5H2Cl2N4, more information about the compound(2,6-Dichloropurine) is in the article, you can click the link below.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem