139009-66-8, (S)-N-Boc-2,2-dimethyloxazolidine-4-carboxylic Acid is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 7-amino-6-methoxy-2-(l-methyl-lH-pyrazol-4-yl)-3-(3,4,5- trimethoxybenzoyl)benzo[Z>]furan (entry 21, Table 1) (0.08 Ig, 0.185 mmol), 2,2-dimethyl- 3-(l,l-dimethylethyl-4S-3,4-ozazolidinedicarboxylic acid (0.067g, 0.27 mmol) and N,N- diisopropylethylamine (0.08 ml, 0.46 mmol) in anhydrous CH2Cl2 (1 ml) PyBroP (0.128g, 0.46 mmol) was added at room temperature under N2. The resulting mixture was stirred for Ih at room temperature, than diluted to 15 ml with ethyl acetate and washed with 10% aqueous citric acid (1 ml), water, brine and dried over anhydrous MgSO4 and filtered off. The filtrate was evaporated to dryness under reduced pressure and the residue was purified by flash column chromatography (silica-gel, CH2Cl2/ ethyl acetate 9:1) giving the title compound (0.106g, 87%) as a creamy solid. 1H NMR (300 MHz, CDCl3) 8.09 (s, IH), 7.93 (s, IH), 7.13 (s, 2H), 7.03 (d, J = 8.75 Hz, IH), 6.8 (d, J = 8.75 Hz, IH), 4.1 -4.7 (broad m, 2H), 3.91 (s, 3H), 3.89 (s, 3H), 3.87 (s, 3H), 3.82 (s, 3H), 3.77 (s, 6H), 3.33 (m, IH), 1.23 – 1.7 (m, 14H)., 139009-66-8
139009-66-8 (S)-N-Boc-2,2-dimethyloxazolidine-4-carboxylic Acid 6932187, aoxazolidine compound, is more and more widely used in various fields.
Reference£º
Patent; ILIAD CHEMICALS PTY LTD; WO2006/84338; (2006); A1;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem