Simple exploration of 452339-73-0

452339-73-0, 452339-73-0 (R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one 10933894, aoxazolidine compound, is more and more widely used in various fields.

452339-73-0, (R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A solution of (5R)-5-(2, 2-dimethyl-4H-1, 3-benzodioxin-6-yl)-1, 3-oxazolidin-2-one (Example 1 viii) (503mg) in DMF (10mL) was treated with sodium hydride (60% dispersion in mineral oil) (97mg) under nitrogen for 20 min. A solution of 1-[2-(benzyloxy) ethoxy] -4- (2-bromoethyl) benzene (676mg) in DMF (5 mL) was added and the reaction stirred for a further 2 h. The reaction mixture was concentrated in vacuo then the residue was prified by chromatography (Biotage, 40g) eluting with EtOAc-petroleum ether (2: 3) to give the title compound (585mg). LCMS RT = 3.66 min

452339-73-0, 452339-73-0 (R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one 10933894, aoxazolidine compound, is more and more widely used in various fields.

Reference£º
Patent; GLAXO GROUP LIMITED; WO2003/91204; (2003); A1;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem