Sep 2021 News Archives for Chemistry Experiments of 102029-44-7

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102029-44-7, Name is (R)-4-Benzyl-2-oxazolidinone, belongs to oxazolidine compound, is a common compound. Electric Literature of 102029-44-7In an article, once mentioned the new application about 102029-44-7.

Two expeditious and efficient syntheses (in 7 and 4 steps, respectively) are described for the central amino acid part of the vancomycin family. The first method constitutes a concise asymmetric synthesis, starting from 4- hydroxyphenylacetic acid, of (R)-(3,5-dihydroxy-4-methoxyphenyl)glycine derivatives using Evans’ asymmetric azidation methodology. In the second approach, an efficient synthesis of a protected 3,5-dichloro-4- methoxyphenylglycine derivative is described, starting from commercially available (R)-4-hydroxyphenylglycine. These two syntheses are much shorter and operationally simpler than those previously described, and are currently employed in an effort towards the construction of the bicyclic system of vancomycin and ristocetin.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1975NO – PubChem