The Absolute Best Science Experiment for Oxazolidin-2-one

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SDS of cas: 497-25-6, Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. In a article, 497-25-6, molcular formula is C3H5NO2, introducing its new discovery.

The development of an intermolecular and enantioselective aza-Wacker reaction is described. Using indoles as the N-source and a selection of alkenols as the coupling partners selective beta-hydride elimination toward the alcohol was achieved. This strategy preserves the newly formed stereocenter by preventing the formation of traditionally observed enamine products. Allylic and homoallylic alcohols with a variety of functional groups are compatible with the reaction in high enantioselectivity. Isotopic-labeling experiments support a syn amino-palladation mechanism for this new class of aza-Wacker reactions.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H288NO – PubChem