Synthetic Route of 497-25-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 497-25-6, Name is Oxazolidin-2-one,introducing its new discovery.
Three illustrative examples are presented from our own approaches to development of drug candidates based on structure-activity relationship analyses. Starting from a lead, 3-(S)-n-butyl-phthalide, an anticonvulsive principle, isolated from Chinese celery seeds, a number of congeners were synthesized and tested. Quantitative structure-activity relationship (QSAR) analyses revealed that the potency depends upon the configuration of substituents around the chiral center at the 3-position, in addition to the hydrophobicity and electronic structure of compounds, and the polarity of substituents in the aromatic moiety. RS-3-n-Butyl-6-amino-phthalide was selected as a candidate for antiepileptic drug. A series of modifications of an antipeptic-ulcer prototype, furazolidone, led to deduction of a lead skeleton. A series of related (hetero) aromatic aldehyde (thio) semicarbazones were synthesized and tested. The QSAR analyses showed that the activity is significantly dependent on the electron density of the (thio) carbonyl group, which is enhanced by the introduction of electrons-donating substituents. Hepatoprotective biphenyl compounds with structures simplified from that of an active principle of a Chinese traditional medicine, were investigated by the analysis of structural parameters obtained from their X-ray crystallography and UV spectrum. The structural requirements for activity were suggested from their configuration and conformation.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 497-25-6, and how the biochemistry of the body works.Synthetic Route of 497-25-6
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H578NO – PubChem