Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Safety of (S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate. Introducing a new discovery about 1676-86-4, Name is (S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate
A series of amphiphilic diblock copolypeptides (K30-b-F15, K30-b-F30, and K30-b-F45) were synthesized via N-carboxy-alpha-amino-anhydride ring-opening polymerization. The copolypeptides had excellent antibacterial efficacy to both Gram positive (S. aureus) and Gram negative (E. coli) bacteria. The minimum inhibitory concentrations (MICs) against E. coli and S. aureus are 8 mug mL?1 and 2 mug mL?1, respectively, lower than most natural and artificial antimicrobial peptides (AMPs). The morphological changes of the bacteria treated with diblock copolypeptides were investigated by transmission electron microscopy; the results proved that the diblock copolypeptides had a similar antibacterial pore-forming mechanism to natural cationic peptides. This was confirmed by laser scanning confocal microscope images. CCK-8 results and the MICs showed that the diblock copolypeptides have high selectivity to bacteria, which suggested that the diblock copolypeptides could be excellent candidates to replace traditional antibiotics in future.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Safety of (S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate, you can also check out more blogs about1676-86-4
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H2738NO – PubChem