Application of 189028-95-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.189028-95-3, Name is (S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one, molecular formula is C20H20FNO4. In a Patent，once mentioned of 189028-95-3
One method for synthesizing intermediate folds Mai Bu (by machine translation)
The invention discloses a method for the synthesis of the intermediates folds Mai Bu , the synthesis method with compound I as the raw material, the compound is mixed with the reaction solution I, fu Suanji and under the action of the, compound I is first extra valeryl chlorine activation, then and S-4-phenyl-2-oxazolidine alkone coupling , the (R)-2-methyl-CBS-oxazole borane reduction reaction, after-treatment is the (4S)-3-[ (5S)-5-(4-fluoro phenyl)-5-hydroxy- fifth heavenly stem acyl group ]-4-phenyl -1, 3-oxygen nitrogen heterocyclic pentane-2-one (II); Wherein the reaction solution comprises tetrahydrofuran, chloroform, dioxane or dichloromethane. The invention discloses one method for synthesizing intermediate folds Mai Bu has the advantages of simple operation, the synthetic route is short, the advantages of synthetic low cost, is suitable for large-scale industrial production. (by machine translation)
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 189028-95-3
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2847NO – PubChem