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Process for the preparation of 5-hydroxymethyl 2-oxazolidinone and novel intermediate

A process for preparing 5-hydroxymethyl-2-oxazolidinone (1), preferably optically active, in one step from 3,4-boronic acid ester protected 3,4-dihydroxybutyramides (2) is described. The oxazolidinone is important in the pharmaceutical industry especially in the areas of antimicrobials and behavioral disorders.

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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1298NO – PubChem