Electric Literature of 6704-31-0, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 6704-31-0, Name is Oxetan-3-one, SMILES is O1CC(C1)=O, belongs to oxazolidines compound. In a article, author is Xiong Ya-Jin, introduce new discover of the category.
Effect of Ionic-Strength and pH Value in Mobile Phase on Enantio-Separation of BSA High Performance Liquid Chromatography Column
BSA chiral columns were prepared based on column modification method with carbonyl imidazole as cross-linker. Enantioseparation of tryptophan, pidotimod and 4-phenyl-1,3-oxazolidine-2-thione (L-ben) was obtained on the BSA chiral column by HPLC. The effects of pH values and ionic strength of mobile phase on enantioseparation performance were investigated. For L-tryptophan, the retention factor (k’) increased significantly as the pH value increased from 5.0 to 7.0. While for D-tryptophan k’ rarely changed and the resolution factor (R-s) increased from 1.15 to 8.91. In contrast, the retention factor (k’) for RS- and SR-pidotimod decreased as the pH value increased from 5.0 to 7.0. For L-ben, k’ was only a slight increase when the pH value increased. The retention factors of three enantiomers fluctuated as ionic strength increased. However, Rs decreased when a buffer concentration increased.
Electric Literature of 6704-31-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 6704-31-0.
Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem